HuagongsheHuagongshe Chemistry Print Report · For research reference only
Myristyl bromide → HCID 53836653, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Myristyl bromide | HCID 8208 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 2-(3-fluoro-4-hydroxyphenyl)acetate | HCID 10797559 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 53836653 | HCID 53836653 | 97.5% |
Reaction Steps
A mixture of 23.0 g of product from Example 60, 34.6 g of 1-bromotetradecane, 54.6 g of potassium carbonate and 250 ml of acetone is heated at reflux temperature for 48 hours. The cooled reaction is filtered and concentrated in vacuo. The residue is purified by column chromatography (silica gel:0-4.5% ethyl acetate/hexane) to give 46.3 g of the desired product as colorless prisms.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208247 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-e851d14c4b2f472b8dd663dffaa6d5e5 |
| Source note | uspto-grants-1993_05 |