HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → N-Acetyl-4-(decyloxy)-3-(1,1-dimethylethyl)-N-(2-pyridinylmethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-(pyridin-2-ylmethyl)acetamide | HCID 5084090 | — |
| Reactant | HCID 19015278 | HCID 19015278 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-Acetyl-4-(decyloxy)-3-(1,1-dimethylethyl)-N-(2-pyridinylmethyl)benzamide | HCID 10367290 | 45.4% |
Reaction Steps
The title compound is prepared by the procedure of Example 27, using 2.9 g of product from Example 132, 1.3 g of product from Example 12, 0.433 g of 50% sodium hydride and 60 ml of dry tetrahydrofuran. The residue is purified by chromatography to give 1.74 g of the desired product as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208247 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-061ef5782fca4c15b8b17a1b64c1c77d |
| Source note | uspto-grants-1993_05 |