Iodoethane → HCID 10394507, compound

HRID 248032Notes

Reaction equation

HRID 248032 reaction equation
[C:1]([N:4]([CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][N:32]=1)[C:5](=[O:29])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])=[C:8]([O:27][CH3:28])[CH:7]=1)(=[O:3])[CH3:2].[CH2:37]([I:39])[CH3:38]>>[I-:39].[C:1]([N:4]([CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][N+:32]=1[CH2:37][CH3:38])[C:5](=[O:29])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])=[C:8]([O:27][CH3:28])[CH:7]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 10097364HCID 10097364, compound

Product 1

HCID 10394507HCID 10394507, compoundYield 75.3%

Conditions

Temperature
105 °C

Procedure

A mixture of 1.01 g of product from Example 49 and 15.83 g of ethyl iodide is heated at 105° C. for 23 hours. The reaction is concentrated in vacuo and triturated with diethyl ether to give 1.0 g of the desired product as yellow crystals.

Workup

  1. concentrationThe reaction is concentrated in vacuo
  2. customtriturated with diethyl ether

Sources & evidence

ORD record
ord-5043da6c6f1642f4a835e3ea75b719e1
Source dataset
uspto-grants-1993_05
Patent number
US05208247

Reaction notes

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