HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 4-[[Acetyl[3-(1,1-dimethylethyl)-4-(tetradecyloxy)benzoyl]amino]methyl]-1-methylpyridinium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | N-Acetyl-3-(1,1-dimethylethyl)-4-(tetradecyloxy)-N-(4-pyridinylmethyl)benzamide | HCID 10481861 | — |
| Product | 4-[[Acetyl[3-(1,1-dimethylethyl)-4-(tetradecyloxy)benzoyl]amino]methyl]-1-methylpyridinium iodide | HCID 10484536 | 97.5% |
Reaction Steps
A mixture of 0.225 g of product from Example 138 and 6.11 g of methyl iodide is heated in a sealed tube, in the dark, at 105° C. for 18 hours. The reaction is concentrated in vacuo to give 0.279 g of the desired product as orange crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208247 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-b2b80013b89545fba021af8cc5b6ac34 |
| Source note | uspto-grants-1993_05 |