反应详情

2,6-bis(1,1-Dimethylethyl)-4-mercaptophenol (36.4 g, 0.15 mole) was dissolved in methanol (250 ml) in a 1 liter, round bottom, 3-necked flask equipped with a stirrer, gas inlet and gas outlet. The solution was flushed with argon and freshly distilled acrolein (25 g, 0.45 mole) and triethylamine (2.4 ml) were added dropwise over a one hour period and the solvent was evaporated on a rotary evaporator and the product purified by chromatography over silica, m.p. ca. 64°-65° C.

1. customround bottom, 3-necked flask equipped with a stirrer, gas inlet and gas outlet
2. additionwere added dropwise over a one hour period
3. customthe solvent was evaporated on a rotary evaporator
4. customthe product purified by chromatography over silica, m.p. ca. 64°-65° C.