huagongshe.com
HRID248092

反应详情

EQUATION

反应方程式

HRID 248092 的结构方程式

REACTANTS

反应物

2
结构：C1COCCO1
HCID31275

1,4-Dioxane

C4H8O2

结构：CCCn1c(=O)c2nc(C(C)Cc3ccc(OCC(=O)N[C@@H](C)C(=O)OC(C)(C)C)cc3)[nH]c2n(CCC)c1=O
HCID178456502

未命名化合物

PRODUCTS

生成物

1
结构：CCCn1c(=O)c2nc(C(C)Cc3ccc(OCC(=O)N[C@@H](C)C(=O)O)cc3)[nH]c2n(CCC)c1=O
HCID178456501

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cl
溶剂HCID313

Hydrochloric Acid

ClH

PROCEDURE

实验过程

Dissolve (-)-N-[[[4-[2-(2,3,6,9-tetrahydro-1,3-dipropyl-2,6-dioxo-1H-purin-8-yl)propy]phenyl]oxy]acetyl]-L-alanine, t-butyl ester (5.55 g, 10 mmol) in 4N hydrochloric acid in dioxane (25 mL, 100 mmol) and stir for several hours. Evaporate the solvent in vacuo and purify by ion-exchange chromatography to give the title compound.

WORKUP

后处理

  1. customEvaporate the solvent in vacuo
  2. custompurify by ion-exchange chromatography