HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-Mercaptophenyl)-4-methoxytetrahydropyran → 4-Methoxy-4-[3-(1,1,3,3-tetramethyl-2,2-dioxo-1,3-dihydrobenzo[c]thien-5-ylthio)phenyl]tetrahydropyran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-Mercaptophenyl)-4-methoxytetrahydropyran | HCID 19375715 | — |
| Reactant | 5-Iodo-1,1,3,3-tetramethyl-1,3-dihydrobenzo[c]thiophene-2,2-dioxide | HCID 19764866 | — |
| Product | 4-Methoxy-4-[3-(1,1,3,3-tetramethyl-2,2-dioxo-1,3-dihydrobenzo[c]thien-5-ylthio)phenyl]tetrahydropyran | HCID 19764772 | 28% |
Reaction Steps
Using a similar procedure to that described in Example 12, 5-iodo-1,1,3,3-tetramethyl-1,3-dihydrobenzo[c]thiophene-2,2-dioxide was reacted with 4-(3-mercaptophenyl)-4-methoxytetrahydropyran to give 4-methoxy-4-[3-(1,1,3,3-tetramethyl-2,2-dioxo-1,3-dihydrobenzo[c]thien-5-ylthio)phenyl]tetrahydropyran in 28% yield, m.p. 133°-135° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208259 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-c3ea584493d44837a28f5fdb04ae1625 |
| Source note | uspto-grants-1993_05 |