HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-(Hexadecylthio)-1-propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Lithium borohydride | HCID 4148881 | — |
| Reactant | Ethyl 3-(hexadecylthio)propanoate | HCID 19764352 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(Hexadecylthio)-1-propanol | HCID 17831703 | 99.1% |
Reaction Steps
To a slurry of 147 mg of lithium borohydride in 20 ml of tetrahydrofuran is added slowly with stirring 2.4 g of ethyl 3-(hexadecylthio)propanoate. The mixture is refluxed for 18 hours and poured into water. A few drops of hydrochloric acid is added followed by ether extraction. The organic layer is dried and evaporated to give 2.1 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208223 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-0b3b8887de5b4ea48f366a80854b492f |
| Source note | uspto-grants-1993_05 |