反应详情

To a slurry of 147 mg of lithium borohydride in 20 ml of tetrahydrofuran is added slowly with stirring 2.4 g of ethyl 3-(hexadecylthio)propanoate. The mixture is refluxed for 18 hours and poured into water. A few drops of hydrochloric acid is added followed by ether extraction. The organic layer is dried and evaporated to give 2.1 g of the desired product.

1. temperatureThe mixture is refluxed for 18 hours
2. extractionfollowed by ether extraction
3. customThe organic layer is dried
4. customevaporated