Hydrazine → HCID 15670095, compound

Participants

Reaction Steps

2.9 ml (0.06 mol) of hydrazine are added to 11.3 g (0.03 mol) of 2-{3-[3-(phenoxymethyl)-1-piperidyl]propyl}-1H-isoindole-1,3(2H)-dione in 226 ml of EtOH. The mixture is heated to the refluxing temperature while stirring for 3 h. It is left to cool and filtered, the filter is rinsed with EtOH and the filtrate is concentrated. The residue is taken up with ether. The filtrate is concentrated and 4.6 g of yellow oil are obtained.

Provenance & Evidence