Hydrochloric Acid → HCID 178422345, compound

Participants

Reaction Steps

2-Methyl-4-acetylpyrazolo[1,5-a]benzimidazole (11), (0.25 g, 1.17 mmol), was added to a mixture of concentrated hydrochloric acid (0.5 ml) in ethanol (5 ml) and heated to reflux for 20 minutes. The solution was cooled to room temperature and poured into a solution of sodium bicarbonate in water (30 ml) to afford a light tan solid which was filtered off, washed and dried, mp. 248°-252° C., 0.20 g, 99%. This was shown by comparative thin layer chromatography and infra-red analysis to be identical to an authentic sample of 2-methylpyrazolo-[1,5-a]benzimidazole (6).

Provenance & Evidence