Tert-Butylamine → HCID 67877334, compound

HRID 248435Notes

Reaction equation

HRID 248435 reaction equation
[Cl:1][C:2]1([Cl:14])[CH:4]([C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:3]1(C)[CH:11]=O.S([O-])([O-])(=O)=O.[Na+].[Na+].[C:22]([NH2:26])([CH3:25])([CH3:24])[CH3:23]>C1C=CC=CC=1>[Cl:1][C:2]1([Cl:14])[CH:4]([C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:3]1[CH3:11].[CH2:2]=[N:26][C:22]([CH3:25])([CH3:24])[CH3:23]

Participants

5

Reactant 3

HCID 6385Tert-ButylamineHCID 24436Sodium SulfateHCID 14924959HCID 14924959, compound

Product 1

HCID 67877334HCID 67877334, compoundYield 159.4%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent3×

Procedure

1.3 g (0.0057 mol) of 2,2-dichloro-1-methyl-3-phenylcyclopropane carbaldehyde were dissolved in 16 ml of anhydrous benzene. The resulting benzene solution was admixed with 0.5 g of anhydrous sodium sulfate, and stirred. To the benzene solution was dropwise added a solution of 2.0 g (0.027 mol) of t-butylamine in 4 ml of the same solvent over 15 minutes. After further stirring for 94 hours, the reaction mixture was filtered to remove the inorganic substances therefrom. Then the benzene and the t-butylamine were distilled off under a reduced pressure to obtain 1.3 g of 2,2-dichloro-1-methyl-3-phenylcyclopropane-methylidene-t-butylamine as an oily substance with light yellow color. Yield: 81%.

Workup

  1. stirringAfter further stirring for 94 hours
  2. filtrationthe reaction mixture was filtered
  3. customto remove the inorganic substances
  4. distillationThen the benzene and the t-butylamine were distilled off under a reduced pressure

Sources & evidence

ORD record
ord-11314afed7074f52a5a92cc4a504c77e
Source dataset
uspto-grants-1993_05
Patent number
US05210218

Reaction notes

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