3,4,5-Triethoxybenzoic acid → HCID 20095703, compound

HRID 248548Notes

Reaction equation

HRID 248548 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([O:16][CH2:17][CH3:18])[C:12]=1[O:13]CC)[C:7]([OH:9])=[O:8])[CH3:2]>Br.C(O)(=O)C>[CH2:17]([O:16][C:11]1[CH:10]=[C:6]([CH:5]=[C:4]([O:3][CH2:1][CH3:2])[C:12]=1[OH:13])[C:7]([OH:9])=[O:8])[CH3:18]

Participants

4

Reactant 1

HCID 814323,4,5-Triethoxybenzoic acid

Product 1

HCID 20095703HCID 20095703, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 260Hydrogen BromideSolvent

Procedure

100 g of 3,4,5-triethoxybenzoic acid was dissolved in 150 ml of a 48% aqueous HBr solution and 300 ml of acetic acid, and the resultant solution was heated at 100° C. for 2 hr while stirring. The reaction mixture was cooled, and the formed precipitate was separated by filtration and washed with water. The solid was recrystallized from 1 l of ethanol to prepare 50 g of the product compound as a white solid.

Workup

  1. temperatureThe reaction mixture was cooled
  2. customthe formed precipitate was separated by filtration
  3. washwashed with water
  4. customThe solid was recrystallized from 1 l of ethanol
  5. customto prepare 50 g of the product compound as a white solid

Sources & evidence

ORD record
ord-6ce3814ee2074401a3f2b9c3fdc9a3cb
Source dataset
uspto-grants-1993_05
Patent number
US05210239

Reaction notes

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