HCID 69740376, compound → 4-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]benzoic acid

HRID 24855Notes

Reaction equation

HRID 24855 reaction equation
[C:1]1(=[O:25])[N:5]([CH2:6][C:7]2[CH:19]=[CH:18][C:10]([C:11]([O:13]C(C)(C)C)=[O:12])=[CH:9][CH:8]=2)[C:4](=[O:20])[C:3]2=[CH:21][CH:22]=[CH:23][CH:24]=[C:2]12>FC(F)(F)C(O)=O>[C:4]1(=[O:20])[N:5]([CH2:6][C:7]2[CH:19]=[CH:18][C:10]([C:11]([OH:13])=[O:12])=[CH:9][CH:8]=2)[C:1](=[O:25])[C:2]2=[CH:24][CH:23]=[CH:22][CH:21]=[C:3]12

Participants

3

Reactant 1

HCID 69740376HCID 69740376, compound

Product 1

HCID 7475534-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]benzoic acid

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

337 mg (1.0 mmol) of tert.butyl 4-phthalimidomethyl-benzoate are stirred in 3 ml of trifluoroacetic acid for 45 minutes at ambient temperature. Then the solvent is eliminated in vacuo.

Sources & evidence

ORD record
ord-14660ef7db7c4a9aa77eb24b2026c98d
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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