4-(2-Ethoxycarbonylmethylamino-ethyl)-aniline → HCID 178472705, compound

HRID 24879Notes

Reaction equation

HRID 24879 reaction equation
C(O[C:4](=[C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[C:17]([N+:20]([O-:22])=[O:21])[CH:18]=2)[NH:13][C:12]1=[O:23])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)C.[CH2:24]([O:26][C:27]([CH2:29][NH:30][CH2:31][CH2:32][C:33]1[CH:39]=[CH:38][C:36]([NH2:37])=[CH:35][CH:34]=1)=[O:28])[CH3:25]>CN(C=O)C>[CH2:24]([O:26][C:27]([CH2:29][NH:30][CH2:31][CH2:32][C:33]1[CH:39]=[CH:38][C:36]([NH:37]/[C:4](=[C:11]2\[C:12](=[O:23])[NH:13][C:14]3[C:19]\2=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][CH:15]=3)/[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=2)=[CH:35][CH:34]=1)=[O:28])[CH3:25]

Participants

4

Reactant 2

HCID 225693114-(2-Ethoxycarbonylmethylamino-ethyl)-anilineHCID 537348873-(1-Ethoxy-1-phenylmethylidene)-5-nitro-2-indolinone

Product 1

HCID 178472705HCID 178472705, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Examples 43 and 89 from 3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-(2-ethoxycarbonylmethylamino-ethyl)-aniline in DMF.

Sources & evidence

ORD record
ord-18b37116d75f47d4b7d98e581fdaf010
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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