反应详情

A mixture of the title compound of Step 15 (2.00 g, 7.51 mmol) and 20% Pd(OH)2 /C in MeOH (50 mL) was placed under a hydrogen atmosphere (60 psi) at room temperature for 37 hours. The filtrate was concentrated to give the title compound as a clear, yellow oil (1.34 g). The proton NMR spectral data showed that the desired product was contaminated with a small amount of unreacted starting material (5%).

1. customat room temperature
2. customfor 37 hours
3. concentrationThe filtrate was concentrated