4-(N-ethoxycarbonylmethyl-N-methylsulphonyl-amino)-aniline → HCID 178472670, compound

HRID 24893Notes

Reaction equation

HRID 24893 reaction equation
C(O[C:4](=[C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[C:17]([N+:20]([O-:22])=[O:21])[CH:18]=2)[NH:13][C:12]1=[O:23])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)C.[CH2:24]([O:26][C:27]([CH2:29][N:30]([C:35]1[CH:41]=[CH:40][C:38]([NH2:39])=[CH:37][CH:36]=1)[S:31]([CH3:34])(=[O:33])=[O:32])=[O:28])[CH3:25]>CN(C=O)C>[CH2:24]([O:26][C:27]([CH2:29][N:30]([C:35]1[CH:36]=[CH:37][C:38]([NH:39]/[C:4](=[C:11]2\[C:12](=[O:23])[NH:13][C:14]3[C:19]\2=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][CH:15]=3)/[C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=2)=[CH:40][CH:41]=1)[S:31]([CH3:34])(=[O:33])=[O:32])=[O:28])[CH3:25]

Participants

4

Reactant 2

HCID 225695884-(N-ethoxycarbonylmethyl-N-methylsulphonyl-amino)-anilineHCID 537348873-(1-Ethoxy-1-phenylmethylidene)-5-nitro-2-indolinone

Product 1

HCID 178472670HCID 178472670, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Examples 89 and 187 from 3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-(N-ethoxycarbonylmethyl-N-methylsulphonyl-amino)-aniline in DMF.

Sources & evidence

ORD record
ord-9019dfc024614f648ef0003d5d3d4837
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

Loading…