N-cyano-O-phenyl-N'-[3-(3-(piperidinomethyl)phenoxy]propyl]isourea → N-cyano-N'-[2-[N-[3-phenyl-3-(2-pyridyl)propyl]-N-methylamino]ethyl]-N"-[3-[3-(piperidinomethyl)phenoxy]propyl]guanidine

Participants

Reaction Steps

Preparation is effected analogously to Example 1, using 0.7 g (2.6 mmol) of N-methyl-N-[3-phenyl-3-(2-pyridyl)propyl]-1,2-ethanediamine and 1 g (2.5 mmol) of N-cyano-O-phenyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]isourea as starting materials. Working up by chromatography (eluant: ethyl acetate) analogously to Example 1 yields the purified title compound in the form of a viscous oil; MS (+FAB method): m/z (rel. int.[%])=568 ([M+H]+ 3), 196 (100).

Provenance & Evidence