HRID248942

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：N#CNC(=NCCCOc1cccc(CN2CCCCC2)c1)Oc1ccccc1

HCID13486636

未命名化合物

HCID19762593

未命名化合物

PRODUCTS

生成物

结构：CN(CCNC(=NCCCOc1cccc(CN2CCCCC2)c1)NC#N)CCC(c1ccccc1)c1ccccn1

HCID54164813

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

Preparation is effected analogously to Example 1, using 0.7 g (2.6 mmol) of N-methyl-N-[3-phenyl-3-(2-pyridyl)propyl]-1,2-ethanediamine and 1 g (2.5 mmol) of N-cyano-O-phenyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]isourea as starting materials. Working up by chromatography (eluant: ethyl acetate) analogously to Example 1 yields the purified title compound in the form of a viscous oil; MS (+FAB method): m/z (rel. int.[%])=568 ([M+H]+ 3), 196 (100).

WORKUP

后处理

customPreparation
custompurified title compound in the form of a viscous oil

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1a906bae9ec44e9a8ebb911a545e4030
来源数据集: uspto-grants-1993_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05212187
来源说明: uspto-grants-1993_05

反应 SMILES

[CH3:1][N:2]([CH2:6][CH2:7][CH:8]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)[CH2:3][CH2:4][NH2:5].[C:21]([NH:23][C:24](=[N:32][CH2:33][CH2:34][CH2:35][O:36][C:37]1[CH:42]=[CH:41][CH:40]=[C:39]([CH2:43][N:44]2[CH2:49][CH2:48][CH2:47][CH2:46][CH2:45]2)[CH:38]=1)OC1C=CC=CC=1)#[N:22]>C(OCC)(=O)C>[C:21]([NH:23][C:24]([NH:5][CH2:4][CH2:3][N:2]([CH2:6][CH2:7][CH:8]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)[CH3:1])=[N:32][CH2:33][CH2:34][CH2:35][O:36][C:37]1[CH:42]=[CH:41][CH:40]=[C:39]([CH2:43][N:44]2[CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]2)[CH:38]=1)#[N:22]