1,1'-Carbonyldiimidazole → HCID 178483435, compound

Participants

Reaction Steps

Preparation is effected analogously to Example 63, using 0.85 g (2.5 mmol) of N-methyl-N-[3-phenyl-3-(2-pyridyl)propyl]-1,7-heptanediamine, an equimolar amount of 1,1'-carbonyldiimidazole and 0.65 g (2.8 mmol) of 2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethaneamine as starting materials. Working up by chromatography (eluant: methylene chloride) analogously to Example 63 yields the purified title compound in the form of an oil; MS (+FAB method): m/z (rel. int.[%])=597 ([M+H]+, 7), 196 (100); IR (KBr): 1655 cm-1 (C=O).

Provenance & Evidence