HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178484614, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-Bromo-N,N-dimethylacetamide | HCID 225544 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | N-[4-[[(Z)-(1-acetyl-5-nitro-2-oxoindol-3-ylidene)-phenylmethyl]amino]phenyl]benzenesulfonamide | HCID 178473951 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178484614 | HCID 178484614 | — |
Reaction Steps
Prepared analogously to Examples 82 and 187 from (Z)-1-acetyl-3-[1-(4-phenylsulphonylamino-phenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone, bromoacetic acid-N,N-dimethylamide and potassium tert.butoxide in DMSO and subsequent treatment with sodium hydroxide solution in methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06855710B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-c1e58ccacf284affa8f5bc6c466b275e |
| Source note | uspto-grants-2005_02 |