反应详情

Preparation is effected analogously to Example 63, using 0.56 g (1.8 mmol) of N-[2-[N-(4-fluorobenzyl)-N-(2-pyridyl)amino]ethyl]-N-methyl-1,2-ethanediamine and the equimolar amounts of 1,1'-carbonyldiimidazole and 2-[[5-[(dimethylamino)methyl]-furfuryl]thio]ethylamine as starting materials. Working up by chromatography analogously to Example 1 yields the purified title compound in the form of a viscous oil; MS(+FAB method): m/z (rel. int. [%])=543 ([M+H]+, 14), 109 (100); IR (KBr): 1641 cm-1 (C=O). For further analysis, a portion of the compound is converted into the O,O'-ditoluoyltartaric acid salt and recrystallised from isopropanol/ether; m.p.: 90° C. (isopropanol/ether).

1. customPreparation
2. customWorking up by chromatography analogously to Example 1 yields the
3. custompurified title compound in the form of a viscous oil
4. customrecrystallised from isopropanol/ether