Sodium Hydroxide → HCID 178483248, compound

HRID 24911Notes

Reaction equation

HRID 24911 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13](Cl)[C:14]2[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][CH:15]=2)[C:5]1=[O:24])(=O)C.[CH3:25][N:26]([CH2:28][C:29]1[CH:35]=[CH:34][C:32]([NH2:33])=[CH:31][CH:30]=1)[CH3:27].[OH-].[Na+]>CN(C=O)C.CO>[CH3:27][N:26]([CH2:28][C:29]1[CH:30]=[CH:31][C:32]([NH:33]/[C:13](=[C:6]2\[C:5](=[O:24])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[CH:10][CH:11]=3)/[C:14]2[CH:15]=[CH:16][C:17]([N+:20]([O-:22])=[O:21])=[CH:18][CH:19]=2)=[CH:34][CH:35]=1)[CH3:25]

Participants

6

Reactant 3

HCID 14798Sodium HydroxideHCID 308051Benzenemethanamine, 4-amino-N,N-dimethyl-HCID 69743555HCID 69743555, compound

Product 1

HCID 178483248HCID 178483248, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Example 2 from 1-acetyl-3-[1-chloro-1-(4-nitrophenyl)-methylidene)-2-indolinone and 4-dimethylaminomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

Sources & evidence

ORD record
ord-9f499830c5884b82b28b6e60d8865a2d
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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