HuagongsheHuagongshe Chemistry Print Report · For research reference only
hexahydro-2H-cyclopenta[b]furan-2-one → HCID 12645859, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | hexahydro-2H-cyclopenta[b]furan-2-one | HCID 11665410 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 12645859 | HCID 12645859 | — |
Reaction Steps
The compound (52) (12.1 g) was reduced with diisobutylaluminum hydride (1.5M, 65.1 ml) in toluene (500 ml) at -78° C. and the obtained crude product was subjected to silicagel column chromatography to give the titled compound (53). Yield: 11.1 g (91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05212324 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-2863b25a99c34b2eab7783f4c5b30bec |
| Source note | uspto-grants-1993_05 |