Sodium Hydroxide → HCID 178483258, compound

HRID 24912Notes

Reaction equation

HRID 24912 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][C:9]([N+:13]([O-:15])=[O:14])=[CH:10][CH:11]=2)[C:6](=[C:16](Cl)[C:17]2[CH:22]=[CH:21][C:20]([N+:23]([O-:25])=[O:24])=[CH:19][CH:18]=2)[C:5]1=[O:27])(=O)C.[CH3:28][N:29]([CH2:31][C:32]1[CH:38]=[CH:37][C:35]([NH2:36])=[CH:34][CH:33]=1)[CH3:30].[OH-].[Na+]>CN(C=O)C.CO>[CH3:30][N:29]([CH2:31][C:32]1[CH:38]=[CH:37][C:35]([NH:36]/[C:16](=[C:6]2\[C:5](=[O:27])[NH:4][C:12]3[C:7]\2=[CH:8][C:9]([N+:13]([O-:15])=[O:14])=[CH:10][CH:11]=3)/[C:17]2[CH:18]=[CH:19][C:20]([N+:23]([O-:25])=[O:24])=[CH:21][CH:22]=2)=[CH:34][CH:33]=1)[CH3:28]

Participants

6

Reactant 3

HCID 14798Sodium HydroxideHCID 308051Benzenemethanamine, 4-amino-N,N-dimethyl-HCID 865915861-Acetyl-3-[1-chloro-1-(4-nitrophenyl)-methylidene)-5-nitro-2-indolinone

Product 1

HCID 178483258HCID 178483258, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Example 2 from 1-acetyl-3-[1-chloro-1-(4-nitrophenyl)-methylidene)-5-nitro-2-indolinone and 4-dimethylaminomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

Sources & evidence

ORD record
ord-f0332a1d5b174ac3984fe42695ef294b
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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