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Phenacylamine → 2-Aminoacetophenone 3-chlorophenylhydrazone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenacylamine | HCID 11952 | — |
| 反応物 | (3-Chlorophenyl)hydrazine | HCID 75332 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-Aminoacetophenone 3-chlorophenylhydrazone | HCID 86746350 | 86.1% |
反応手順
A mixture of 3.12 g 2-aminoacetophenone and 3.29 g 3-chlorophenylhydrazine in 4 ml HOAc and 20 ml EtOH was refluxed for one hour. The cooled reaction mixture was diluted with water and the precipitate was collected, washed with water, and dried to give 5.16 g solid. Recrystallization from methanol gave 2.12 g solid, m.p. 131°-134° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05214059 |
| 出典データセット | uspto-grants-1993_05 |
| ORD ID | ord-f0fb4ee128634fbc8c8d3a1e252fae6f |
| 出典メモ | uspto-grants-1993_05 |