Hydrochloric Acid → HCID 18677745, compound

HRID 249347Notes

Reaction equation

HRID 249347 reaction equation
C([N:4]1[CH2:9][CH2:8][CH:7]([N:10]([CH3:21])[C:11](=[O:20])[O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:6][CH2:5]1)(=O)C.[ClH:22]>CO>[ClH:22].[NH:4]1[CH2:5][CH2:6][CH:7]([N:10]([CH3:21])[C:11](=[O:20])[O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:8][CH2:9]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19761266Carbamic acid, (1-acetyl-4-piperidinyl)methyl-, phenylmethyl ester

Product 1

HCID 18677745HCID 18677745, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

14.5 g of the compound obtained in Stage B are refluxed with 50 ml of methanol and 30 ml of 6N hydrochloric acid for 20 hours. After evaporation the hydrochloride of the desired product is obtained.

Workup

  1. customAfter evaporation the hydrochloride of the desired product
  2. customis obtained

Sources & evidence

ORD record
ord-fa64d8f772a34f74be068f58d834722c
Source dataset
uspto-grants-1993_05
Patent number
US05214055

Reaction notes

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