HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 249510Generated: October 25, 2026
Methyl isothiocyanate → N-methyl-N'-ethyl-N'-(3-pyridylmethyl)thiourea
https://huagongshe.com/reaction/249510
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl isothiocyanate | HCID 11167 | — |
| Reactant | Ethyl[(pyridin-3-yl)methyl]amine | HCID 4716480 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | N-methyl-N'-ethyl-N'-(3-pyridylmethyl)thiourea | HCID 22450434 | 100.3% |
Reaction Steps
In 50 ml of ethyl ether was dissolved 2.4 g of N-ethyl-N-(3-pyridylmethyl)amine followed by addition of 1.3 g of methyl isothiocyanate. The mixture was stirred at room temperature (25° C.) for 1 hour. The resulting precipitate was collected by filtration, washed with a small amount of ethyl ether and dried to give 3.7 g of N-methyl-N'-ethyl-N'-(3-pyridylmethyl)thiourea as white prisms.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05214152 |
|---|
| Source dataset | uspto-grants-1993_05 |
|---|
| ORD ID | ord-44541d504266468eb6785c420de3fa6e |
|---|
| Source note | uspto-grants-1993_05 |
|---|
