Methylamine → HCID 59896603, compound

HRID 249524Notes

Reaction equation

HRID 249524 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C:9](SC)=[CH:10][N+:11]([O-:13])=[O:12])=[CH:4][CH:3]=1.[CH3:16][NH2:17]>CCO.CO>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C:9]([NH:17][CH3:16])=[CH:10][N+:11]([O-:13])=[O:12])=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 6329MethylamineHCID 85593012HCID 85593012, compound

Product 1

HCID 59896603HCID 59896603, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 887MethanolSolvent

Procedure

In 25 ml of EtOH was dissolved 0.42 g (0.00171 mole) of 1-(6-chloro-3-pyridyl)amino-1-methylthio-2-nitroethylene, followed by addition of 0.2 g of a 40% solution of methylamine in methanol. The mixture was refluxed for 1.5 hours. The solvent was distilled off and the crystalline residue was washed with AcOEt and dried to recover 0.33 g of the title compound as white crystals.

Workup

  1. temperatureThe mixture was refluxed for 1.5 hours
  2. distillationThe solvent was distilled off
  3. washthe crystalline residue was washed with AcOEt
  4. customdried
  5. customto recover 0.33 g of the title compound as white crystals

Sources & evidence

ORD record
ord-df9e29f92e964c5b8ee4eb0ed7a2b596
Source dataset
uspto-grants-1993_05
Patent number
US05214152

Reaction notes

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