HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-Chloroquinoline-3-carboxylate → Ethyl 4-chloro-6,7-difluoroquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-Chloroquinoline-3-carboxylate | HCID 268963 | — |
| Reactant | HCID 178469610 | HCID 178469610 | — |
| Product | Ethyl 4-chloro-6,7-difluoroquinoline-3-carboxylate | HCID 1511944 | — |
Reaction Steps
The title compound was prepared following the procedure described in Step 2 for the synthesis of 3a using 2c instead of 2a. 1H NMR (CDCl3) δ (ppm): 1.47 (3H, t, J=7.08 Hz), 4.56 (2H, q, J=7.08 Hz), 7.72 (1H, d, J=8.79 Hz), 8.39 (1H, d, J=8.78 Hz), 9.23 (1H, s). m/z 271.6/273.6 (M+/M+2). m/z 272.6 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863266B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-28805ef310544126840c05c3fc5c7d40 |
| Source note | uspto-grants-2011_01 |