Ethylorthoformate → HCID 135846125, compound

Participants

Reaction Conditions

Reaction Steps

(6E)-3-Pentyl-8-(trifluoromethyl)-3,7-dihydro-1H-purine-2,6-dione-6-hydrazone (0.15 g, 0.20 mmol) was mixed with ethyl orthoformate (2 mL, 10 mmol). The mixture was heated at 100° C. for 30 min, concentrated under reduced pressure and purified by preparative HPLC to yield the desired product. LCMS calculated for C12H14F3N6O (M+H): 315.1. found: 315.1.

Provenance & Evidence