反应详情

To a solution of 6-isobutyl-6,7-dihydro-5h-[1,2,4]triazolo[3,4-i]purin-5-one (9.4 mg, 40 mmol) in THF (5 ml) was added N-bromosuccinimide (8 mg, 44.7 mmol). The mixture was stirred at room temperature for 30 minutes. The reaction mixture was concentrated, and the residue was purified by preparative LCMS (method A) to provide the desired product. LCMS calculated for CO10H12BrN6O (M+H): 311.0. found 310.9, 313.0.

1. concentrationThe reaction mixture was concentrated
2. customthe residue was purified by preparative LCMS (method A)