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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 249842Generated: November 1, 2026

(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride → HCID 66873775, compound

https://huagongshe.com/reaction/249842

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochlorideHCID 12494973—
ReactantHCID 66873324HCID 66873324—
ProductHCID 66873775HCID 66873775—

Reaction Steps

Following general procedure GP-C1, a mixture of 2-(pyridin-4-ylamino)benzoxazole-4-carboxylic acid and (S)-(−)-3-aminoquinuclidine dihydrochloride were coupled to provide (S)—N-(quinuclidine-8-yl)-2-(pyridin-4-ylamino)benzoxazole-4-carboxamide, which was converted to the dihydrochloride salt following general procedure GP-D1. 1H NMR and MS consistent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07863271B2
Source datasetuspto-grants-2011_01
ORD IDord-a0a680c7f71f4cbf8f5820a6d796aa77
Source noteuspto-grants-2011_01