Lithium hydroxide, monohydrate → HCID 66874572, compound

HRID 249901Notes

Reaction equation

HRID 249901 reaction equation
[C:1]([N:4]1[CH2:9][C@H:8]([CH3:10])[N:7]([C:11]2[O:12][C:13]3[C:14](=[C:16]([C:20]([O:22]C)=[O:21])[CH:17]=[CH:18][CH:19]=3)[N:15]=2)[C@@H:6]([CH3:24])[CH2:5]1)(=[O:3])[CH3:2].O.[OH-].[Li+:27]>>[C:1]([N:4]1[CH2:9][C@H:8]([CH3:10])[N:7]([C:11]2[O:12][C:13]3[C:14](=[C:16]([C:20]([O-:22])=[O:21])[CH:17]=[CH:18][CH:19]=3)[N:15]=2)[C@@H:6]([CH3:24])[CH2:5]1)(=[O:3])[CH3:2].[Li+:27]

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 66874258HCID 66874258, compound

Product 1

HCID 66874572HCID 66874572, compound

Procedure

Following general procedure GP-B2, methyl 2-((2S,6S)-4-acetyl-2,6-dimethylpiperazin-1-yl)benzoxazole-4-carboxylate was reacted with lithium hydroxide monohydrate to provide lithium 2-((2S,6S)-4-acetyl-2,6-dimethylpiperazin-1-yl)benzoxazole-4-carboxylate. 1H NMR and MS consistent.

Sources & evidence

ORD record
ord-9a0eb9cab11d48e58986688fb6f171db
Source dataset
uspto-grants-2011_01
Patent number
US07863271B2

Reaction notes

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