HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Methoxy-2-methyl-phenyl)-benzo[b]thiophene-7-carboxylic acid methyl ester → 2-(4-Hydroxy-2-methyl-phenyl)-benzo[b]thiophene-7-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Methoxy-2-methyl-phenyl)-benzo[b]thiophene-7-carboxylic acid methyl ester | HCID 67271921 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(4-Hydroxy-2-methyl-phenyl)-benzo[b]thiophene-7-carboxylic acid methyl ester | HCID 67272514 | 69% |
Reaction Steps
The title compound (85 mg, 69%) is prepared essentially as described in the synthesis of 2-(4-Hydroxy-2-methyl-phenyl)-benzo[h]thiophene-5-carboxylic acid ethyl ester, utilizing 2-(4-Methoxy-2-methyl-phenyl)-benzo[b]thiophene-7-carboxylic acid methyl ester and methanol. ES/MS m/e 297 (M−1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863302B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-d998b5b7f64146f8bbabdf1a57f4ee4f |
| Source note | uspto-grants-2011_01 |