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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 250580Generated: November 2, 2026

5-isopropenyl-1H-pyrrolo[2,3-b]pyridine → 5-isopropyl-1H-pyrrolo[2,3-b]pyridine

https://huagongshe.com/reaction/250580

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-isopropenyl-1H-pyrrolo[2,3-b]pyridineHCID 58086810—
CatalystPalladium hydroxideHCID 9942167—
SolventTetrahydrofuranHCID 8028—
Product5-isopropyl-1H-pyrrolo[2,3-b]pyridineHCID 59928720—

Reaction Steps

To 5-isopropenyl-1H-pyrrolo[2,3-b]pyridine (98, 0.080 g, 0.501 mmol) in tetrahydrofuran (5.0 mL) was added 20% palladium hydroxide on carbon (5.0 mg). The reaction was stirred under hydrogen at 40 psi for 30 minutes. The reaction mixture was filtered and concentrated to give the compound (99, 0.078 g, 96%). MS (ESI) [M+H+]+=161.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07863288B2
Source datasetuspto-grants-2011_01
ORD IDord-84a60f407a9849fc9ad2560c8d4b7ffe
Source noteuspto-grants-2011_01