HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 25077Generated: October 30, 2026
Methyl bromoacetate → HCID 22565520, compound
https://huagongshe.com/reaction/25077
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | (+/-)-8-Methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-carbothiohydrazide | HCID 12137411 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22565520 | HCID 22565520 | 37.3% |
Reaction Steps
A mixture of 1.00 g (2.50 mmol) of the starting material XVIII, 20 ml of dimethylformamide and 0.94 g (6.14 mmol) of methyl bromoacetate was stirred at 70° C. for 1.5 h. After dilution with water the precipitated crystals were filtered off and purified by refluxing in ethyl acetate to yield 0.41 g (37%) of the title compound; Mp.: 294-295° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06858605B2 |
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| Source dataset | uspto-grants-2005_02 |
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| ORD ID | ord-ef5d2a6d94954bcbb77a4dc951caacb0 |
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| Source note | uspto-grants-2005_02 |
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