huagongshe.com
HRID251011

反应详情

EQUATION

反应方程式

HRID 251011 的结构方程式

REACTANTS

反应物

3
结构：O=Cc1nccc2ccccc12
HCID265306

isoquinoline-1-carbaldehyde

C10H7NO

结构：CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+]
HCID5049666

Sodium triacetoxyborohydride

C6H10BNaO6

结构：Cc1cnc(CNCCCCN(C)C(=O)OC(C)(C)C)c(C)c1
HCID58997083

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(CN(CCCCN(C)C(=O)OC(C)(C)C)Cc2nccc3ccccc23)c(C)c1
HCID67273128

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Using General Procedure B: Reaction of {4-[(3,5-Dimethyl-pyridin-2-ylmethyl)-amino]-butyl}-methyl-carbamic acid tert-butyl ester and 1-isoquinoline-carbaldehyde with NaBH(OAc)3 in CH2Cl2 gave {4-[(3,5-Dimethyl-pyridin-2-ylmethyl)-isoquinolin-1-ylmethyl-amino]-butyl}-methyl-carbamic acid tert-butyl ester as a yellow oil.