HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-(4-aminobutyl)carbamate → [4-(1-Pyridin-2-ylethylamino)-butyl]-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-(4-aminobutyl)carbamate | HCID 4351 | — |
| Reactant | 2-Acetylpyridine | HCID 14286 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Product | [4-(1-Pyridin-2-ylethylamino)-butyl]-carbamic acid tert-butyl ester | HCID 67272354 | — |
Reaction Steps
Using General Procedure B, (4-aminobutyl)-carbamic acid tert-butyl ester and 2-acetylpyridine in CH2Cl2 and NaBH(OAc)3 were reacted to obtain [4-(1-pyridin-2-ylethylamino)-butyl]-carbamic acid tert-butyl ester as a light brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863293B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-960e056838fd46e3b373f312a207c171 |
| Source note | uspto-grants-2011_01 |