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HRID251103

反应详情

EQUATION

反应方程式

HRID 251103 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)CCCN1C(=O)c2ccccc2C1=O
HCID236270

2-(4-Oxopentyl)-1H-isoindole-1,3(2H)-dione

C13H13NO3

结构：CC(N)c1ccccn1
HCID541877

1-(2-Pyridinyl)ethanamine

C7H10N2

结构：CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+]
HCID5049666

Sodium triacetoxyborohydride

C6H10BNaO6

PRODUCTS

生成物

1
结构：CC(CCCN1C(=O)c2ccccc2C1=O)NC(C)c1ccccn1
HCID67272300

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Using General Procedure B: Reaction of 2-(4-oxo-pentyl)-isoindole-1,3-dione (Abdel-Monem, M M et al. J. Med. Chem. 1974, 17, 447-451) in CH2Cl2 and 1-pyridin-2-yl-ethylamine with NaBH(OAc)3 gave 2-[4-(1-pyridin-2-yl-ethylamino)-pentyl]-isoindole-1,3-dione as a colorless oil.