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HRID251503

反应详情

EQUATION

反应方程式

HRID 251503 的结构方程式

REACTANTS

反应物

4
结构：COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC
HCID5770

Reserpine

C33H40N2O9

结构：Nc1ccc(Br)cn1
HCID70622

2-Amino-5-bromopyridine

C5H5BrN2

结构：COc1ccc(Br)cc1NC(=O)OC(C)(C)C
HCID17942658

未命名化合物

结构：CCCCCCC.CCOC(C)=O
HCID21899848

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)Nc1ccc(Br)cn1
HCID16217843

tert-Butyl (5-bromopyridin-2-yl)carbamate

C10H13BrN2O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

The compound was prepared from 5-bromo-2-pyridinamine in the manner described for compound (2): 1H NMR (DMSO-d6, 400 MHz) δ 9.96 (s, 1H), 8.49 (d, 1H), 7.93 (dd, 1H), 7.78 (d, 1H), 1.47 (s, 9H); TLC (ethyl acetate/heptane 5:95) Rf 0.28; RP-HPLC (Hypersil HyPurity Elite C18, 5 μm, 200 A, 250×4.6 mm; 25-100% acetonitrile-0.1 M ammonium acetate over 25 min, 1 ml/min) tr=18.50 min.