反应详情

温度

0 °C

27.4 g (0.1 mol) of the compound from Example XXI are dissolved in 200 ml of tetrachloromethane and the solution is heated to boiling. After addition of 0.82 g of azobisisobutyronitrile, 18.7 g (0.105 mol) of N-bromosuccinimide are added in portions and the mixture is then refluxed for 1 h, cooled to 0° C. and succinimide is filtered off. After concentrating the filtrate the product precipitates. It is washed with petroleum ether (40/60) and dried.

1. temperaturethe solution is heated to boiling
2. additionare added in portions
3. temperaturethe mixture is then refluxed for 1 h
4. filtrationsuccinimide is filtered off
5. concentrationAfter concentrating the filtrate the product
6. customprecipitates
7. washIt is washed with petroleum ether (40/60)
8. customdried