反应详情

Raney-Ni (cat.) and NH3.H2O (4˜5 drops) were added to the solution of 3-(imidazo[1,2-b]pyridazin-2-yl)benzonitrile (25 mg) in MeOH. The mixture was stirred vigorously at room temperature for 1 h under hydrogen and the Raney-Ni was then removed. The filtration was concentrated in vacuo to give the (3-(imidazo[1,2-b]pyridazin-2-yl)phenyl)methanamine.

1. customthe Raney-Ni was then removed
2. filtrationThe filtration
3. concentrationwas concentrated in vacuo