HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 11625924, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Chlorobutyryl chloride | HCID 78370 | — |
| Reactant | HCID 59682846 | HCID 59682846 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 11625924 | HCID 11625924 | — |
Reaction Steps
Analogously to example 36, 2-(8-bromo-6-chloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylamine (80 mg) was reacted with 4-chlorobutyryl chloride (35 mg) and the resulting amide was subsequently ring-closed with potassium carbonate in DMSO.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07868003B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-17442275a0b0400094896c2809542f17 |
| Source note | uspto-grants-2011_01 |