Hydrazine hydrate (1:1) → HCID 178499521, compound

HRID 251954Notes

Reaction equation

HRID 251954 reaction equation
C[N:2](C)[CH:3]=[CH:4][C:5](=O)[CH:6]([O:9][CH3:10])[O:7][CH3:8].O.[NH2:14]N>CO>[CH3:8][O:7][CH:6]([O:9][CH3:10])[C:5]1[CH:4]=[CH:3][NH:2][N:14]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 27821454-(Dimethylamino)-1,1-dimethoxybut-3-en-2-one

Product 1

HCID 178499521HCID 178499521, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 5 g of 4-dimethylamino-1,1-dimethoxy-3-butene-2-one, 1.7 ml of hydrazine monohydrate and 15 ml of methanol was stirred for 8 hours under heat refluxing. The reaction mixture was concentrated under reduced pressure to obtain 4.07 g of 3-(dimethoxymethyl)-1H-pyrazole of the formula:

Workup

  1. temperatureunder heat
  2. temperaturerefluxing
  3. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-9709df6c10be494a900ae6bbb024a05c
Source dataset
uspto-grants-2011_01
Patent number
US07867949B2

Reaction notes

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