HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Pyridinecarboxylic acid, 6-(4-amino-1-piperidinyl)-, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Tert-butoxycarbonylamino-1-(5-ethoxycarbonyl-pyrid-2-yl) piperidine | HCID 22574446 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-Pyridinecarboxylic acid, 6-(4-amino-1-piperidinyl)-, ethyl ester | HCID 11402429 | — |
Reaction Steps
The product of stage b) is dissolved in ethyl acetate, a 3N solution of hydrochloric acid in ethyl acetate is added and the mixture is left stirring at ambient temperature for 10 hours. The product is filtered off and washed with acetone. The title product is obtained. M.p.: 148-150° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06858629B1 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-007fab9badaf4c7ca8c9d853d77769da |
| Source note | uspto-grants-2005_02 |