Triphenylphosphine → HCID 86618874, compound

HRID 252353Notes

Reaction equation

HRID 252353 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][I:7].[C:8]1([P:14]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>C(#N)C>[I-:7].[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][P+:14]([C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 227078941-Iodo-4-methoxybutane

Product 1

HCID 86618874HCID 86618874, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

10.70 g of 4-methoxybutyl iodide are taken up in 80 ml of acetonitrile. 14.43 g of triphenylphosphine are added and the reaction solution is heated to reflux for 16 hours. The reaction solution is concentrated by evaporation and the residue is admixed with diethyl ether. The suspension is stirred at room temperature for 30 minutes and the precipitated solid is filtered off and dried. The title compound is used for the next stage without further purification.

Workup

  1. temperaturethe reaction solution is heated
  2. temperatureto reflux for 16 hours
  3. concentrationThe reaction solution is concentrated by evaporation
  4. filtrationthe precipitated solid is filtered off
  5. customdried
  6. customThe title compound is used for the next stage without further purification

Sources & evidence

ORD record
ord-2f6205ad7b3c4ee39a1f1f71d1310d5b
Source dataset
uspto-grants-2011_01
Patent number
US07868036B2

Reaction notes

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