反应详情

NaH (60%, 400 mg, 10 mmol) was added to ethanol (10 mL) and stirred at room temperature for 30 min. Then, 4-fluoro-2-nitro-5-phenoxy-benzaldehyde (520 mg, 2 mmol) was added. The resulting mixture was stirred at room temperature overnight and ten concentrated. The resulting crude mixture was purified by chromatography (silica gel, 20-50% methylene chloride in heptane) to yield a slightly yellow solid.

1. stirringThe resulting mixture was stirred at room temperature overnight
2. concentrationten concentrated
3. customThe resulting crude mixture was purified by chromatography (silica gel, 20-50% methylene chloride in heptane)
4. customto yield a slightly yellow solid