HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-(trifluoromethyl)pyrimidine → N-(4-cyano-1-methyl-piperidin-4-yl)-2-(4-trifluoromethyl-pyrimidin-2-ylamino)-3-cyclohexyl-propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-(trifluoromethyl)pyrimidine | HCID 2773912 | — |
| Reactant | 2-amino-N-(4-cyano-1-methyl-piperidin-4-yl)-3-cyclohexyl-propionamide | HCID 22063143 | — |
| Product | N-(4-cyano-1-methyl-piperidin-4-yl)-2-(4-trifluoromethyl-pyrimidin-2-ylamino)-3-cyclohexyl-propionamide | HCID 22063357 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-trifluoromethyl pyrimidine and 2-amino-N-(4-cyano-1-methyl-piperidin-4-yl)-3-cyclohexyl-propionamide according to the procedure from Example 19. MS, m/z 439.5=M+1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06858623B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-b66c3efcf9364c67b55dbd1f48029e72 |
| Source note | uspto-grants-2005_02 |