反应详情

温度

60 °C

2-(3′,4′-dimethylbiphenyl-3-yl)-9-hydroxyl-3H-naphtho[1,2-d]imidazole-7-sulfonic acid hydrochloride(0.08 g, 0.18 mmol) was suspended in 1 ml thionyl chloride containing catalytic amount of N,N-dimethylformamide. The reaction mixture was heated to 60° C. for 3 hours then was concentrated to dryness to give 2-(3′,4′-dimethylbiphenyl-3-yl)-9-hydroxyl-3H-naphtho[1,2-d]imidazole-7-sulfonyl chloride.

1. concentrationthen was concentrated to dryness